Publications 2012

Below you will find links to the publications from the year 2012 which describe research financed by the BLUEPRINT project.

     
     
    Mol Oncol
    December 2012

 
   J Medicinal Chem
   December 2012

 
  Molecular Cell
  December 2012

 
    Trials with ‘epigenetic’
   drugs: an update

    Discovery of salermide-
    related sirtuin inhibitors:
    binding mode studies...

 
  The dynamics of genome
  -wide DNA methylation
  reprogramming in mouse...
 
     
  
   Biochimie
   November 2012

 
  
   Chem Med Chem
   November 2012

 
   
   Front Genet
   December 2012

 
   Identification of PR-
   SET7 and EZH2
   selective inhibitors...

   Carprofen analogues
   as Sirtuin Inhibitors:
   enzyme and cellular...
   miRNA-mediated deregulation
   in leukemia
 









 
   
   Brit J Haematol
   October 2012
   Genome Research
   November 2012

 
   Genome Research
   November 2012

 
   Genome-wide DNA
   methylation profiling
   predicts relapse in...

 
   A functional methylome
   map of ulcerative colitis
   Guthrie card methylomics
   identifies temporally stable
   epialleles that are present...
 








 
   










 
   Nature Genetics
   October 2012


   Nature Genetics
   October 2012

 
  Genome Biology
  October 2012

 
   Epigenetic polymorphism
   and the stochastic
   formation of differentially..

   Epigenomic analysis
   detects widespread
   gene-body DNA ...
   EpiExplorer: live exploration
   and global analysis of large
   epigenomic datasets











 
   
  
   Nat Rev Genetics
   October 2012

 
  Clin Cancer Res
  October 2012
   
    Epigenetics
    October 2012
   DNA methylation profiling
   in the clinic: applications
   and challenges
  Molecular pathways: the
  complexity of the
  epigenome in cancer...
    Human-specific CpG
    “beacons” identify loci
    associated with ...













 

   Proc Natl Acad Sci USA
   August 2012
   Genome Biology
   August 2012

    J Med Chem
    September 2012

 
   Amino acid starvation
   induces reactivation of
   silenced transgenes...

 
   Genome-wide distribution
   of 5-formylcytosine in
   embryonic stem cells...
   Benzodeazaoxaflavins as
   sirtuin inhibitors with anti-
   proliferative properties...
 











 
 

 
 
   Nat Cell Biol
   July 2012
   Epigenetics
   August 2012

 
   Mol Cancer
   August 2012
   The H19 lincRNA is a
   developmental reservoir of
   miR-675 that suppresses...
   Report on the Infinium
   450k Methylation Array
   Analysis Workshop...
   The emerging role of histone
   lysine demethylases in prostate
   cancer


 
 







 



 


 
 
   
   Nat Rev Cancer
   July 2012

 
  
   ChemMedChem
   July 2012
  
   Giga Science
   July 2012

 
    Managing drug resistance
    in cancer: lessons from
    HIV therapy

 
   Design, synthesis, and
   biological evaluation of
   2-Aminobenzanilide...
    Resources for methylome
    analysis suitable for gene
    knockout studies of....












 
 

   Nat Biotechnol
   March 2012

 
   Science
   May 2012
   Epigenetics
   June 2012

 
   BLUEPRINT to decode
   the epigenetic signature
   written in blood

 
   Quantitative sequencing of
   5-Methylcytosine and 5-
   Hydrozymethylcytosine....
   Whole Genome bisulfite
   DNA sequencing of a
   DNMT3B mutant patient











 












 
 
  
   Nucleus
   March 2012

 

   Med Chem Commun
   March 2012

   Nature Protoc
   March 2012
   Chromatin signatures of
   active enhancers
   Developing novel non-
   hydroxamate histone
   deacetylase inhibitors...

   Methylome analysis using
   MeDIP-seeq with low DNA
   concentrations



 














 
 













 
     Front Pharmacol
   January 2012

 
   J Mol Biol
   February 2012
     Sirtuins and disease: the
   road ahead



 
    An analog of BIX-01294
    selectively inhibits a family
    of histone H3 lysine 9 ../