Fourth data release

17 March 2014

Monocytes and neutrophils are the most abundant white cells in peripheral blood and essential components of the innate immune system, which comprises the first line of defense against infection. Although both are derived from the myelomonocytic progenitor cell and have similar functions as phagocytes and cytokine producing cells, monocyte are immature cells that have additional functions in antigen presenting and the capacity to further differentiate into macrophages.

The fourth Blueprint data release is now available. Within Blueprint we isolated cells from 4 bone marrow, 14 peripheral blood, 22 cord blood, 1 tonsil and 1 cell line sample and performed epigenomic analysis including RNA-seq, DNAme-seq, DNAseI-seq and 8 different ChIP-seq experiments. This fourth release includes data on monocytes, granulocyte neutrophils, macrophage (M0, M1 and M2), naive CD4+ and naive CD8+ cells and a cell line (U-266).

Future releases of data for additional samples are planned at a regular basis.

Information about the reuse of data generated by the EC funded FP7 High Impact Project, Blueprint can be found via the following link.

Information about data access for non-BLUEPRINT members can be found via the following link.